Biochemistry ( Free PDF )

Cover image
Title page
Copyright
Preface to the Fourth Edition
Preface to the First Edition
Acknowledgements
Scope of Biochemistry
Section One: Chemical Constituents of Life
Chapter 1: Biomolecules and the Cell
Chapter 2: Carbohydrates
Summary
Monosaccharides—structural aspects Structure of glucose
Disaccharides
Polysaccharides
Homopolysaccharides
Heteropolysaccharides
Agar and pectin
Glycoproteins
Self-assessment exercises
Chapter 3: Lipids
Summary
Fatty acids
Essential fatty acids
Triacylglycerols
Phospholipids
Glycolipids
Lipoproteins
Steroids
Amphipathic lipids
Soaps and detergents
Self-Assessment exercises
Chapter 4: Proteins and Amino Acids
Summary
Amino acids
Structure of proteins
Self-assessment exercises
Chapter 5: Nucleic Acids and Nucleotides
Chapter 6: Enzymes
Chapter 7: Vitamins
Section Two: Physiological Biochemistry
Chapter 8: Digestion and Absorption
Chapter 9: Plasma Proteins
Chapter 10: Hemoglobin and Porphyrins
Chapter 11: Biological Oxidation
Section Three: Metabolisms
Chapter 12: Introduction to Metabolism
Chapter 13: Metabolism of Carbohydrates
Chapter 14: Metabolism of Lipids
Chapter 15: Metabolism of Amino Acids
Chapter 16: Integration of Metabolism
Chapter 17: Metabolism of Nucleotides
Chapter 18: Mineral Metabolism
Section Four: Clinical Biochemistry and Nutrition
Chapter 19: Hormones
Chapter 20: Organ Function Tests
Chapter 21: Water
Chapter 22: Tissue Proteins and Body Fluids
Chapter 23: Nutrition
Section Five: Molecular Biology and Biotechnology
Chapter 24: DNA-Replication
Chapter 25: Transcription and Translation
Chapter 26: Regulation of Gene Expression
Chapter 27: Recombinant DNA and Biotechnology
Section Six: Current Topics
Chapter 28: Human Genome Project
Chapter 29: Gene Therapy
Chapter 30: Bioinformatics
Chapter 31: Metabolism of Xenobiotics (Detoxification)
Chapter 32: Prostaglandins and Related Compounds
Chapter 33: Biological Membranes and Transport
Chapter 34: Free Radicals and Antioxidants
Chapter 35: Environmental Biochemistry
Chapter 36: Insulin
Chapter 37: Cancer
Chapter 38: Acquired Immunodeficiency Syndrome (AIDS)
Section Seven: Basics to Learn Biochemistry
Chapter 39: Introduction to Bioorganic Chemistry
Chapter 40: Overview of Biophysical Chemistry
Chapter 41: Tools of Biochemistry
Chapter 42: Immunology
Chapter 43: Genetics
Appendix
Index

Preface

This book of ‘Biochemistry’ is undoubtedly one of the most widely read books by both students and teachers of medicine, biology and other allied sciences (in India and many other countries). It is truly an excellent book and a true companion to all biochemists; hence it deserves to be considered by many as the ‘Bible of Biochemistry’. This book has been iterated, revised and revised three times over a period of thirteen years.

Due to the rapid growth of this subject, biological development is also increasing. Also, critical thinking, critical thinking and constructive feedback from teachers and students should be taken into consideration. All this requires regular review of the book.

Review each chapter thoroughly and update it with the latest developments in this fourth edition. The focus of this text is the positive aspect of human biology and its treatment in health and disease. Various experimental and biochemical models (with reviews and discussions) have also been newly added. In addition, many new biological properties are reported in this article, some of which are listed below.

• Triacylglycerol/fatty acid cycle

• Metabolic syndrome

• Glucose toxicity

• Estimated average glucose

• Peptide nucleic acids

• Pseudogenes

• Recombinant ribozymes

• Epigenetic regulation of gene expression

• Metagenomics

• Therapeutic diets

• Atkins diet

• Dietary antioxidants

• High fructose corn syrup

s • ω-fatty acid

• Soluble and insoluble fiber

• Trans fatty acids

• Nutrigenomics

• Detailed information on antivitamins

• Dental caries

• Amino acids as neurotransmitters

• Disorders of membrane transport

• Diagnostic importance of various body fluids and tissues

• Enzyme patterns in diseases

• Cystatin C

• Pleural fluid

• High sensitive CRPIt is a fact that I represent a selected group of individuals authoring books, having some time at disposal, besides hard work, determination and dedication. I consider myself as an eternal reader and a regular student of biochemistry. However, it is beyond my capability to keep track of the evergrowing advances in biochemistry due to exponential growth of the subject. And, this makes me nervous whenever I think of revising the book. I honestly and frankly admit that I have to depend on mature readers for subsequent editions of this book. To readers, well-wishers and experts in Article must admit that it is not always possible to meet readers face to face and listen to their opinions. I sincerely invite readers, well-wishers and biologists to feel free and write to me (email id: uppalasatya@yahoo.com) to express their honest views, critical opinions and constructive comments. This will also help me improve the book in the next review.

Biology is perhaps the most interesting subject because it refers to the chemical expression of life, be it humans, animals, plants or microbes. No other branch of science has as much application as biology in the fields of medicine, health, veterinary medicine, agricultural bioengineering and technology. This requires a completely different approach to the biochemistry literature.

There are many biology books on the market. Some are only important if the other is used, and few books cover both topics together. Therefore, students studying biology have to rely on many books to gain comprehensive knowledge of the subject during college classes.

This book, ‘Biochemistry’ is unique and focuses on the fundamentals and applications of biology. This book is basically a combination of medical science and quality, written entirely to meet the requirements of undergraduate courses in medicine, dentistry, pharmacy, health sciences and other fields (agriculture, veterinary medicine, etc.) where students study biology as one of the basic sciences. topics.

What is common among students (especially in medicine) is to view organisms as normal metabolic pathways that are useful and uncomplicated. This book offers a fresh look at biochemistry so that students can grasp the relevance and relevance of biological applications in medicine.

This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides color illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners.

It is not right to explain here how and when the book was born. The entire book was written in the early hours of the morning (between 2 and 6 a.m., when the world is most asleep), and I do intellectual work during these hours. Fresh thoughts and new ideas full of creative ideas after a good night’s sleep helped me a lot in writing this book. My wife begged me not to write about diabetes, cancer and AIDS at home. In his opinion, I did my best to write these articles in my spare time at the department. But when I went through them in my serene mood of the early morning hours, I had to discard them in disappointment and rewrite them. Truly, each page of this book was conceived in darkness and born at daybreak! This textbook is a distillation of my knowledge and teaching experience in biochemistry, acquired during the past 25 years. It contains predigested information on biochemistry for good understanding, assimilation and reproducibility. Each page is crafted with a fine eye. The ultimate purpose of this book is to equip the reader with comprehensive knowledge in biochemistry with reference to basic as well as applied aspects.

Even though I did my best to make the book error-free, I was not wrong. I welcome feedback, criticism and suggestions from teachers and students.

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